Hans Joenje Selected Research

Mitomycin (Mitomycin-C)

3/2016	Sensitivity to chromosomal breakage as risk factor in young adults with oral squamous cell carcinoma.
1/2012	Diagnosis of fanconi anemia: chromosomal breakage analysis.
1/2007	Identification of the Fanconi anemia complementation group I gene, FANCI.
10/2006	Cellular characterization of cells from the Fanconi anemia complementation group, FA-D1/BRCA2.
1/2006	A case report of a patient with microcephaly, facial dysmorphism, mitomycin-c-sensitive lymphocytes, and susceptibility to lymphoma.
1/2006	Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks.
4/2005	A cross-linker-sensitive myeloid leukemia cell line from a 2-year-old boy with severe Fanconi anemia and biallelic FANCD1/BRCA2 mutations.
10/2003	A novel ubiquitin ligase is deficient in Fanconi anemia.
5/2003	Genetic reversion in an acute myelogenous leukemia cell line from a Fanconi anemia patient with biallelic mutations in BRCA2.
7/2002	Biallelic inactivation of BRCA2 in Fanconi anemia.

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Hans Joenje Research Topics

Disease

30	Fanconi Anemia (Fanconi's Anemia) 11/2015 - 07/2002
19	Hypersensitivity (Allergy) 01/2022 - 02/2002
16	Neoplasms (Cancer) 01/2022 - 07/2002
9	Chromosome Breakage 03/2016 - 02/2002
9	Chromosomal Instability (Chromosome Stability) 12/2015 - 02/2002
6	Genomic Instability 09/2015 - 10/2006
5	Bone Marrow Failure Disorders 12/2015 - 01/2006
5	Complementation Group D1 Fanconi Anemia 10/2006 - 07/2002
3	Squamous Cell Carcinoma of Head and Neck 01/2022 - 02/2005
3	Breast Neoplasms (Breast Cancer) 01/2008 - 05/2003
1	Epidermolysis Bullosa 01/2018
1	Inborn Genetic Diseases (Disease, Hereditary) 12/2015
1	Hyperoxia 12/2015
1	Fanconi Syndrome (Syndrome, Fanconi) 09/2015
1	Anemia 09/2015
1	Roberts Syndrome 02/2010
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2006
1	Microcephaly 01/2006
1	Lymphoma (Lymphomas) 01/2006
1	Complementation Group J Fanconi Anemia 09/2005
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 04/2005
1	Ataxia Telangiectasia (Louis Bar Syndrome) 12/2004
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 06/2004
1	Chromosome Aberrations (Chromosome Abnormalities) 05/2003

Drug/Important Bio-Agent (IBA)

29	DNA (Deoxyribonucleic Acid)IBA 03/2016 - 02/2002
19	Proteins (Proteins, Gene)FDA Link 01/2018 - 03/2002
12	Mitomycin (Mitomycin-C)FDA LinkGeneric 03/2016 - 02/2002
4	A-Form DNA (A-DNA)IBA 01/2010 - 10/2003
3	UbiquitinIBA 07/2012 - 10/2003
3	Fanconi Anemia Complementation Group D2 ProteinIBA 01/2008 - 10/2003
3	Small Interfering RNA (siRNA)IBA 04/2007 - 01/2007
3	Cisplatin (Platino)FDA LinkGeneric 02/2005 - 11/2002
2	Pharmaceutical PreparationsIBA 01/2022 - 02/2010
2	Nuclear Proteins (Protein, Nuclear)IBA 12/2015 - 11/2004
2	Fanconi Anemia Complementation Group ProteinsIBA 11/2015 - 10/2003
2	Ligases (Synthetase)IBA 09/2005 - 10/2003
2	Fanconi Anemia Complementation Group G ProteinIBA 01/2004 - 03/2002
1	N,N'- (2,2'- (hexa- 2,4- diyne- 1,6- diylbis(oxy))bis(2,3- dihydro- 1H- indene- 2,1- diyl))bis(1- (2- cyclohexyl- 2- (2- (methylamino)propanamido)acetyl)pyrrolidine- 2- carboxamide)IBA 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	Aconitate Hydratase (Aconitase)IBA 12/2015
1	Glucose (Dextrose)FDA LinkGeneric 01/2015
1	Oxygen (Dioxygen)IBA 01/2015
1	Carrier Proteins (Binding Protein)IBA 07/2012
1	diepoxybutaneIBA 01/2012
1	EndonucleasesIBA 02/2011
1	Histones (Histone)IBA 03/2010
1	AcetyltransferasesIBA 09/2009
1	CamptothecinIBA 07/2009
1	ChromatinIBA 02/2007
1	Alkylating AgentsIBA 01/2006
1	Archaeal DNAIBA 09/2005
1	DNA HelicasesIBA 09/2005
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 10/2003
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 05/2003
1	Interleukin-3 (Interleukin 3)IBA 05/2003
1	OligonucleotidesIBA 11/2002

Therapy/Procedure

2	Therapeutics 01/2011 - 02/2005
1	Radiotherapy 01/2022
1	Ligation 01/2012